ncRNA name | Hist1h1c siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, immunohistochemical/fluorescence staining, MTT assay, Western blot, qPCR |
Expression pattern | associated |
Functional description | Knockdown of histone Hist1h1c by siRNA in the retinas of diabetic mice significantly attenuated the diabetes-induced autophagy, inflammation, glial activation and neuron loss. |
PubMed ID | 28409999 |
Year | 2017 |
Title | Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy. |
Drug-related ncRNA | NO |
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